Downregulation of caspase 9 is seen in ________________ A. Melanoma

downregulation-of-caspase-9-is-seen-in-a-melanoma

Downregulation of caspase 9 is seen in ________________

A. Melanoma

B. Breast cancer

C. Colorectal cancer

D. Lung cancer

I have been asked this question during an internship interview.

I’m obligated to ask this question of Apoptosis and Cancer topic in chapter Cancer Biology & Methods in Cytogenetics of Cytogenetics

Correct answer is C. Colorectal cancer

Explanation: Reduced functioning of caspases may prevent apoptosis thus leading to cancer. Down regulation of caspase 12 is seen mostly in case of colorectal cancers.