A microclimate pH, different from the luminal pH exists at the

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A microclimate pH, different from the luminal pH exists at the membrane surface.

A. True

B. False

I had been asked this question during an interview.

My question is taken from Drugs Absorption in division Absorption of Drugs of Drug Biotechnology

Right choice is A. True

The explanation: As shown in experiments, pH absorption curves are less steep and shift to left for basic drug and shift to the right for an acidic drug. This led to the hypothesis that a virtual pH also called a microclimate pH exists at the membrane surface.