CpGProD is a web-based program that predicts promoters containing a high density of CpG islands _______
A. in archea genomic sequences
B. in mammalian genomic sequences
C. in eukaryotic and bacterial genomic sequences
D. only in bacterial genomic sequences
I had been asked this question by my school principal while I was bunking the class.
My question is based upon Prediction Algorithms in chapter Promoter and Regulatory Element Prediction of Bioinformatics
Correct answer is B. in mammalian genomic sequences
To explain: It calculates moving averages of GC% and CpG ratios (observed/expected) over a window of a certain size (usually 200 bp). When the values are above a certain threshold, the region is identified as a CpG island.