Downregulation of caspase 3 can lead to ovarian cancer. A. True

downregulation-of-caspase-3-can-lead-to-ovarian-cancer-a-true

Downregulation of caspase 3 can lead to ovarian cancer.

A. True

B. False

I had been asked this question in an interview for job.

Origin of the question is Apoptosis and Cancer in section Cancer Biology & Methods in Cytogenetics of Cytogenetics

Correct choice is A. True

To explain I would say: It has been reported that caspase-3 mRNA levels are appreciably downregulated in breast, ovarian, and cervical tumours. Low levels of caspases or impairment in caspase function may lead to decreased apoptosis.