Deletion of a region led to over expression of a gene X. What

deletion-of-a-region-led-to-over-expression-of-a-gene-x-what

Deletion of a region led to over expression of a gene X. What do you conclude from this observation?

A. Part of gene X is mutated

B. Promoter of gene X is deleted

C. Regulator of gene X is deleted

D. No effect on gene X or its regulators

I have been asked this question in an international level competition.

Question is from Chromosomal Abnormalities : Deletion topic in chapter Chromosomal Basis of Inheritance of Cytogenetics

The correct choice is C. Regulator of gene X is deleted

Explanation: In this case over expression of gene X is due to deletion of some negative regulator like operon, insulator, silencer etc.